Bibliografía científica de los ingredientes Nessum

Esta página recopila estudios científicos reales y verificables sobre los principales ingredientes presentes en la gama Nessum. Cada referencia incluye un enlace directo al estudio original (DOI) para que puedas consultarlo tú misma.

Cimicífuga (Cimicifuga racemosa)

Leach, M. J., & Moore, V. (2012). Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database of Systematic Reviews, 2012(9), CD007244. https://doi.org/10.1002/14651858.CD007244.pub2

Maca (Lepidium meyenii)

Brooks, N. A., et al. (2008). Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women. Menopause, 15(6), 1157-1162. https://doi.org/10.1097/gme.0b013e3181732953

Vitamina B6

Agnew-Blais, J. C., et al. (2015). Folate, Vitamin B6 and Vitamin B12 Intake and Mild Cognitive Impairment and Probable Dementia in the Women's Health Initiative Memory Study. Journal of the Academy of Nutrition and Dietetics, 115(2), 231-241. https://doi.org/10.1016/j.jand.2014.07.006

Zinc

Vázquez-Lorente, H., et al. (2022). Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B12, and folate in a postmenopausal population. Journal of Trace Elements in Medicine and Biology, 71, 126942. https://doi.org/10.1016/j.jtemb.2022.126942

Lúpulo (Humulus lupulus)

Aghamiri, V., et al. (2016). The effect of Hop (Humulus lupulus L.) on early menopausal symptoms and hot flashes: A randomized placebo-controlled trial. Complementary Therapies in Clinical Practice, 23, 130-135. https://doi.org/10.1016/j.ctcp.2015.05.001

Erkkola, R., et al. (2010). A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts. Phytomedicine, 17(6), 389-396. https://doi.org/10.1016/j.phymed.2010.01.007

Salvia (Salvia officinalis)

Bommer, S., Klein, P., & Suter, A. (2011). First time proof of sage's tolerability and efficacy in menopausal women with hot flashes. Advances in Therapy, 28(6), 490-500. https://doi.org/10.1007/s12325-011-0027-z

Vitamina D3 y Calcio

Liu, C., Kuang, X., Li, K., Guo, X., Deng, Q., & Li, D. (2020). Effects of combined calcium and vitamin D supplementation on osteoporosis in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials. Food & Function, 11(12), 10817-10827. https://doi.org/10.1039/D0FO00787K

Tribulus terrestris

de Souza, K. Z. D., Vale, F. B. C., & Geber, S. (2016). Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial. Menopause, 23(11), 1252-1256. https://doi.org/10.1097/GME.0000000000000766

Melatonina

Du, J., & Tan, Y. (2026). A systematic review and meta-analysis of randomized controlled trials investigated the effects of melatonin supplementation on bone mineral density, quality of life, and sleep in menopausal women. Frontiers in Nutrition, 13, 1687221. https://doi.org/10.3389/fnut.2026.1687221

Amstrup, A. K., et al. (2015). The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial. Nutrition Journal. https://doi.org/10.1186/s12937-015-0093-1

L-Teanina

Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M., & Kunugi, H. (2019). Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients, 11(10), 2362. https://doi.org/10.3390/nu11102362

Pasiflora (Passiflora incarnata)

Harit, M. K., et al. (2024). Randomized, Double-Blind, Placebo-Controlled, Clinical Study of Passiflora incarnata in Participants With Stress and Sleep Problems. Cureus, 16(3), e56530. https://doi.org/10.7759/cureus.56530

Magnesio

Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress: A Systematic Review. Nutrients, 9(5), 429.

Vitamina B12

Agnew-Blais, J. C., et al. (2015). Folate, Vitamin B6 and Vitamin B12 Intake and Mild Cognitive Impairment and Probable Dementia in the Women's Health Initiative Memory Study. Journal of the Academy of Nutrition and Dietetics, 115(2), 231-241. https://doi.org/10.1016/j.jand.2014.07.006

Ácido Hialurónico

Dahab, M., & Ibrahim, B. (2026). Hyaluronic acid for vaginal health and quality of life in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials. International Journal of Gynecology & Obstetrics. https://doi.org/10.1002/ijgo.70887

Aloe Vera

Hekmatpou, D., Mehrabi, F., Rahzani, K., & Aminiyan, A. (2019). The effect of Aloe vera clinical trials on prevention and healing of skin wound: A systematic review. Advances in Skin & Wound Care, 32(4), 167-175. https://doi.org/10.1097/01.ASW.0000552427.12943.12

Manzanilla (Matricaria chamomilla)

Valmy, J., et al. (2025). Anti-inflammatory effect of chamomile from randomized clinical trials: a systematic review and meta-analyses. Pharmaceutical Biology, 63(1), 490-502. https://doi.org/10.1080/13880209.2025.2530995

Pantenol (Provitamina B5)

A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential. Journal of Dermatological Treatment (2017). https://doi.org/10.1080/09546634.2016.1214235

Caléndula (Calendula officinalis)

Valmy, J., et al. (2025). Anti-inflammatory effect of chamomile from randomized clinical trials: a systematic review and meta-analyses. Pharmaceutical Biology, 63(1), 490-502. https://doi.org/10.1080/13880209.2025.2530995

Malva (Malva sylvestris)

Meysami, M., Hashempur, M. H., Kamalinejad, M., & Emtiazy, M. (2021). Efficacy of Short Term Topical Malva Sylvestris L. Cream in Pediatric Patients with Atopic Dermatitis: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Endocrine, Metabolic & Immune Disorders Drug Targets, 21(9), 1673-1678. https://doi.org/10.2174/1871530320666201023125411

Alantoína

Czajkowska-Kośnik, A., Bagińska, Z. H., & Winnicka, K. (2024). Emulsions containing allantoin and D-panthenol as attractive moisturizing agents. Acta Poloniae Pharmaceutica, 80(6), 965-976. https://doi.org/10.32383/appdr/174461

Aceite de Onagra (Oenothera biennis)

Evening Primrose Oil for Menopause Hot Flashes: Systematic Review and Meta-Analysis. Journal of Menopausal Medicine. https://doi.org/10.6118/jmm.23038

Rosa Mosqueta (Rosa aff. rubiginosa)

Belkhelladi, M., & Bougrine, A. (2024). Rosehip extract and wound healing: A review. Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.15971

Hamamelis (Hamamelis virginiana)

Wójciak, M., Pacuła, W., Sowa, I., Feldo, M., Graczyk, F., & Załuski, D. (2025). Hamamelis virginiana L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications. Molecules, 30(13), 2744. https://doi.org/10.3390/molecules30132744

Vitamina E

Thongchumnum, W., Vallibhakara, S. A. O., Sophonsritsuk, A., & Vallibhakara, O. (2023). Effect of Vitamin E Supplementation on Chronic Insomnia Disorder in Postmenopausal Women: A Prospective, Double-Blinded Randomized Controlled Trial. Nutrients, 15(5), 1187. https://doi.org/10.3390/nu15051187

Contenido revisado por última vez: julio de 2026.